Activity cliffs in drug discovery: Dr Jekyll or Mr Hyde?

Dr. Jekyll or Mr. Hyde: Information Security in the Ecosystem of Healthcare

“Jekyll and Hyde” embodies how information security affects today’s healthcare ecosystem. When security works, it promotes patient health and a smooth operating ecosystem (Dr. Jekyll); when it doesn’t, privacy and health compromises can occur (Mr. Hyde). In this paper, we argue that unusable security triggers this split personality and in doing so, compromises the heart of the healthcare ecosys...

Scientists and animal research: Dr. Jekyll or Mr. Hyde?

Two Honeysuckles: A Tale of Dr. Jekyll and Mr. Hyde

Lublin Studies in Modern Languages and Literature

The paper engages with Stevenson’s novel The Strange Case of Dr Jekyll and Mr Hyde from the perspective of essential duality embedded in every one’s nature: it explicates the entangling nature of binaries and the aesthetics of non-disjunction of the binary self/Other as embodied in the figures of Dr Jekyll and Mr Hyde respectively. By the novel’s end, the two aspects, the Jekyllean and the Hyde...

Is ascorbate Dr Jekyll or Mr Hyde in the Cu(Aβ) mediated oxidative stress linked to Alzheimer’s disease?†

Evaluation of the pro versus antioxidant activity of ascorbate regarding Cu(Aβ) induced reactive oxygen species production in the context of Alzheimer's disease shows that a protective activity can only be observed at high ascorbate concentration for exogenous molecules but not for the amyloid-β peptide itself.